Broad Panel Assays:
Liquid Trace and Profile Plus Technlogy*
Liquid Trace™ Solid Tumor is a pan-cancer highly sensitive test evaluating 284 cfDNA genes and >1,600 cfRNA genes.
- Can be used for diagnoses, evaluating the host immune response, and identifying biomarkers for predicting response to various therapies.
- Can reduce the need for tissue biopsies for certain cancer patients, especially when obtaining tissue from the tumor is difficult.
Solid Tumor Profile PLUS™ tests for abnormalities in 434 DNA genes and >1,600 RNA genes.
- A pan-tumor assay that can detect all cancer types
- Includes detection of single nucleotide variation, copy number variation, expression, known and novel fusions, exon skipping, alternative splicing
Solid Tumors
Next generation sequencing DNA & RNA testing
Hematology Profile PLUS™ provides a precise diagnosis and classification, combining expression and fusion data with mutation analysis in DNA and RNA. This is a comprehensive evaluation.
- Includes IgVH mutation status
- Viral EBV testing
- Chromosomal abnormalities, translocations and gene amplifications
- T and B-cell clonality
Liquid Trace™ Hematology A pan-cancer highly sensitive test evaluating cfDNA and cfRNA.
- Can be used for diagnoses, classification of all types of hematological malignancies, evaluating the host immune response, and identifying biomarkers for predicting response to various therapies
- Replacement for bone marrow aspirations and biopsy
- Monitoring therapy and response
- Detection of minimal residual disease (MRD)
Hematologic Tumors
Next generation sequencing DNA & RNA testing
Test specifications
| Liquid Trace™: Solid Tumor Profile | Solid Tumor Profile Plus™ | Liquid Trace™: Hematology Profile | Hematology Profile Plus™ | |
|---|---|---|---|---|
| Genes | 284 / >1600 | 434 / >1600 | 284 / >1600 | 284 / >1600 |
| Turnaround time | 5 - 7 days | 7 - 10 days | 5 - 7 days | 7 - 10 days |
| Indications | All solid tumors: Chromosomal abnormalities, gene amplifications, HRR, MRD, Fusions: ALK, ROS1, RET, NTRK1/2/3, and more. BRAF, CIC, EWSR1, PD-L1, MET exon 14 skipping and various alternative splicing, MET, HER2, PIK3CA, PTEN, Gene amplifications, AKT1, RAS, HER2, MYC, EGFR, Cancer of unknown primary (CUP), HPV, T- & B-cell clonality analysis | All solid tumors: Fusions: ALK, ROS1, RET, NTRK1/2/3, and more. BRAF, CIC, EWSR1, PD-L1, MET exon 14 skipping and various alternative splicing, MET, HER2, EGFR, Gene amplifications, PIK3CA, PTEN, AKT1, RAS and HRD Cancer of unknown primary (CUP) T- & B-cell clonality analysis | All hematologic neoplasms including lymphoma multiple myeloma, acute lymphoblastic leukemia, acute myeloid leukemia, MDS, CMML, MPN, MRD, VEXAS syndrome, and EBV Chromosomal abnormalities, and gene amplifications, T- & B-cell clonality analysis | All hematologic neoplasms including lymphoma Classification and diagnosis of lymphoma, multiple myeloma, acute lymphoblastic leukemia, and acute myeloid leukemia Includes IgVH Chromosomal abnormalities, and gene amplifications, T- & B-cell clonality analysis |
| Sample type | Peripheral blood | FFPE | Peripheral blood | Bone marrow, Peripheral blood, Fresh tissue |
| Sample requirements | Peripheral blood: 8-10 mL EDTA tube preferred |
1 H&E slide and 6-8 unstained slides, 5-7 microns of tissue fixed with 10% NBF fixative |
Peripheral blood: 8-10 mL EDTA tube preferred | Bone marrow: 2 mL Peripheral blood: 5 mL EDTA tube preferred FFPE: 1 H&E slide and 6-10 unstained slides, 5-7 microns of tissue fixed with 10% NBF fixative |
| Results reported | DNA+RNA |
DNA+RNA |
DNA+RNA | DNA+RNA |
| Uses | Monitoring; Therapeutic; Prognostic; Heterogeneity; Clinical trial matching | Diagnostic; Therapeutic; Prognostic; Heterogeneity; Clinical trial matching | Diagnostic; Therapeutic; Prognostic; Heterogeneity; Clinical trial matching | Diagnostic; Therapeutic; Prognostic; Heterogeneity; Clinical trial matching |
Genes validated and tested for mutations in DNA testing for solid tumor
| 1-110 | 111-220 | 221-330 | 331-434 |
|---|---|---|---|
| ABCB7 | EP300 | KDM6A | RAD21 |
| ABL1 | EPAS1 | KDR | RAD50 |
| ABL2 | EPCAM | KEAP1 | RAD51 |
| ACD | EPHA3 | KEL | RAD51B |
| ACVR1B | EPHA5 | KIF23 | RAD51C |
| ADA | EPHA7 | KIT | RAD51D |
| AK2 | EPHB1 | KLF1 | RAD54L |
| AKT1 | ERBB2 | KLHL6 | RAF1 |
| AKT2 | ERBB3 | KLLN | RANBP2 |
| AKT3 | ERBB4 | KMT2A | RARA |
| ALK | ERCC4 | KMT2B | RB1 |
| AMER1 | ERG | KMT2C | RBBP6 |
| ANKRD26 | ERRFI1 | KMT2D | RBM10 |
| APC | ESR1 | KRAS | REEP5 |
| AR | ETV6 | LIG4 | RBM8A |
| ARAF | EXO1 | LMO1 | RET |
| ARFRP1 | EZH2 | LPIN2 | RHEB |
| ARID1A | FAM175A | LRP1B | RHOA |
| ARID1B | FAM46C | LYN | RICTOR |
| ARID2 | FANCA | LYST | RIT1 |
| ASXL1 | FANCB | LZTR1 | RNF168 |
| ATG2B | FANCC | MAGI2 | RNF43 |
| ATM | FANCD2 | MAP2K1 | ROS1 |
| ATR | FANCE | MAP2K2 | RPTOR |
| ATRX | FANCF | MAP2K4 | RTEL1 |
| AURKA | FANCG | MAP3K1 | RUNX1 |
| AURKB | FANCI | MAP3K14 | RUNX1T1 |
| AURKC | FANCL | MAPK1 | SAMD9L |
| AXIN1 | FANCM | MCL1 | SBDS |
| AXIN2 | FAS | MDM2 | SBF2 |
| AXL | FAT1 | MDM4 | SDHA |
| B2M | FBXW7 | MED12 | SDHB |
| BAP1 | FGF10 | MEF2B | SDHC |
| BARD1 | FGF14 | MEFV | SDHD |
| BCL2 | FGF19 | MEN1 | SEC23B |
| BCL2L1 | FGF23 | MET | SETBP1 |
| BCL2L2 | FGF3 | MITF | SETD2 |
| BCL6 | FGF4 | MLH1 | SF3B1 |
| BCOR | FGF6 | MPL | SLIT2 |
| BCORL1 | FGFR1 | MRE11A | SLX4 |
| BCR | FGFR2 | MSH2 | SMAD2 |
| BIRC3 | FGFR3 | MSH6 | SMAD3 |
| BLM | FGFR4 | MTOR | SMAD4 |
| BMPR1A | FH | MUTYH | SMAD9 |
| BRAF | FLCN | MVK | SMARCA4 |
| BRCA1 | FLI1 | MYC | SMARCB1 |
| BRCA2 | FLT1 | MYCL | SMC1A |
| BRD4 | FLT3 | MYCN | SMC3 |
| BRIP1 | FLT4 | MYD88 | SMO |
| BTG1 | FOXL2 | NBN | SNCAIP |
| BTK | FOXP1 | NF1 | SOCS1 |
| C11orf30 | FRS2 | NF2 | SOX10 |
| C15ORF41 | FUBP1 | NFE2L2 | SOX2 |
| CALR | G6PC3 | NFKBIA | SOX9 |
| CARD11 | GABRA6 | NHP2 | SPEN |
| CBFB | GALNT12 | NKX2-1 | SPOP |
| CBL | GATA1 | NLRP3 | SPTA1 |
| CBLB | GATA2 | NME1 | SRC |
| CBLC | GATA3 | NOP10 | SRSF2 |
| CCND1 | GATA4 | NOTCH1 | STAG2 |
| CCND2 | GATA6 | NOTCH2 | STAT3 |
| CCND3 | GEN1 | NOTCH3 | STAT4 |
| CCNE1 | GFI1 | NPM1 | STAT6 |
| CD274 | GFI1B | NRAS | STK11 |
| CD79A | GID4 | NROB1 | SUFU |
| CD79B | GLI1 | NSD1 | SUZ12 |
| CDAN1 | GLI2 | NTRK1 | SYK |
| CDC73 | GNA11 | NTRK2 | TAF1 |
| CDH1 | GNA13 | NTRK3 | TAL1 |
| CDK12 | GNAQ | NUP93 | TBX3 |
| CDK4 | GNAS | PAK3 | TCF3 |
| CDK6 | GPR124 | PALB2 | TCIRG1 |
| CDK8 | GREM1 | PARK2 | TERC |
| CDKN1A | GRIN2A | PAX5 | TERF1 |
| CDKN1B | GRM3 | PBRM1 | TERF2 |
| CDKN2A | GSK3B | PDCD1LG2 | TERF2IP |
| CDKN2B | GSKIP | PDGFRA | TERT |
| CDKN2C | H3F3A | PDGFRB | TET2 |
| CEBPA | HAX1 | PDK1 | TGFBR2 |
| CHD2 | HGF | PHF6 | TNFAIP3 |
| CHD4 | HIST1H3B | PIK3C2B | TNFRSF14 |
| CHEK1 | HNF1A | PIK3CA | TNFRSF1A |
| CHEK2 | HOXA11 | PIK3CB | TOP1 |
| CIC | HOXB13 | PIK3CG | TOP2A |
| CREBBP | HRAS | PIK3R1 | TP53 |
| CRKL | HSD3B1 | PIK3R2 | TRAF3 |
| CRLF2 | HSP90AA1 | PIM1 | TSC1 |
| CSF1R | ID3 | PLCG1 | TSC2 |
| CSF3R | IDH1 | PLCG2 | TSHR |
| CTC1 | IDH2 | PMS1 | U2AF1 |
| CTCF | IGF1R | PMS2 | U2AF2 |
| CTNNA1 | IGF2 | POLD1 | VEGFA |
| CTNNB1 | IKBKE | POLE | VHL |
| CUL3 | IKZF1 | POT1 | WAS |
| CUX1 | IKZF3 | PPM1D | WHSC1 |
| CXCR4 | IL2RG | PPP2R1A | WISP3 |
| CYLD | IL7R | PRDM1 | WT1 |
| DAXX | INHBA | PREX2 | XPO1 |
| DDR2 | INPP4B | PRKAR1A | XRCC2 |
| DDX11 | IRF2 | PRKCI | XRCC3 |
| DDX41 | IRF4 | PRKDC | ZBTB2 |
| DICER1 | IRS2 | PRSS1 | ZNF217 |
| DKC1 | JAGN1 | PRSS8 | ZNF703 |
| DNM2 | JAK1 | PSTPIP1 | ZRSR2 |
| DNMT3A | JAK2 | PTCH1 | |
| DOT1L | JAK3 | PTEN | |
| EED | JUN | PTPN11 | |
| EGFR | KAT6A | QKI | |
| EGLN1 | KDM5A | RAB27A | |
| ELANE | KDM5C | RAC1 |
Genes tested for mutations, fusion, and expression levels in cfDNA testing
| 1-60 | 61-120 | 121-180 | 181-240 | 241-284 |
|---|---|---|---|---|
| ABL1 | CREBBP | GNAS | NF2 | SMC3 |
| ACVR1B | CRLF2 | GREM1 | NFE2L2 | SMO |
| AKT1 | CSF1R | GRIN2A | NFKBIA | SOCS1 |
| AKT2 | CSF3R | H3-3A | NKX2-1 | SOX2 |
| AKT3 | CTCF | HGF | NOTCH1 | SOX9 |
| ALK | CTNNA1 | H3C2 | NOTCH2 | SPOP |
| AMER1 | CTNNB1 | HNF1A | NOTCH3 | SRC |
| APC | CUX1 | HOXB13 | NPM1 | SRSF2 |
| AR | CXCR4 | HRAS | NRAS | STAG2 |
| ARAF | CYLD | HSP90AA1 | NSD1 | STAT3 |
| ARID1A | DAXX | ID3 | NTRK1 | STK11 |
| ARID1B | DDR2 | IDH1 | NTRK2 | SUFU |
| ARID2 | DICER1 | IDH2 | NTRK3 | SUZ12 |
| ASXL1 | DNM2 | IGF1R | PAK3 | TAL1 |
| ATM | DNMT3A | IKZF1 | PALB2 | TCF3 |
| ATR | DOT1L | IKZF3 | PAX5 | TERT |
| ATRX | EED | IL7R | PBRM1 | TET2 |
| AURKA | EGFR | INHBA | PDGFRA | TGFBR2 |
| AURKB | EGLN1 | IRF4 | PDGFRB | TNFAIP3 |
| AURKC | EP300 | JAK1 | PHF6 | TNFRSF14 |
| AXIN1 | EPAS1 | JAK2 | PIK3CA | TP53 |
| AXIN2 | EPHA3 | JAK3 | PIK3R1 | TRAF3 |
| B2M | EPHA5 | KAT6A | PIK3R2 | TSC1 |
| BAP1 | ERBB2 | KDM5C | PIM1 | TSC2 |
| BCL2 | ERBB3 | KDM6A | PLCG1 | TSHR |
| BCL2L1 | ERBB4 | KDR | PMS1 | U2AF1 |
| BCL6 | ERG | KEAP1 | PMS2 | U2AF2 |
| BCOR | ESR1 | KIT | POLD1 | VHL |
| BCORL1 | ETV6 | KMT2A | POLE | NSD2 |
| BCR | EXO1 | KMT2B | PPM1D | WT1 |
| BIRC3 | EZH2 | KMT2C | PPP2R1A | XPO1 |
| BLM | ABRAXAS1 | KMT2D | PRDM1 | XRCC2 |
| BRAF | TENT5C | KRAS | PRKAR1A | XRCC3 |
| BRCA1 | FANCA | LRP1B | PRKDC | ZNF217 |
| BRCA2 | FANCC | MAP2K1 | PRSS1 | ZRSR2 |
| BRIP1 | FANCD2 | MAP2K2 | PTCH1 | NFE2 |
| BTK | FANCE | MAP2K4 | PTEN | UBA1 |
| CALR | FANCF | MAP3K1 | PTPN11 | STAT5B |
| CARD11 | FANCG | MAP3K14 | RAC1 | ETNK1 |
| CBL | FAS | MAPK1 | RAD21 | ELANE |
| CBLB | FBXW7 | MCL1 | RAD50 | ANKRD26 |
| CBLC | FGF4 | MDM2 | RAD51 | SAMD9L |
| CCND1 | FGF6 | MDM4 | RAF1 | SAMD9 |
| CCND3 | FGFR1 | MED12 | RB1 | DDX41 |
| CCNE1 | FGFR2 | MEF2B | RET | |
| CD274 | FGFR3 | MEN1 | RHEB | |
| CD79A | FGFR4 | MET | RHOA | |
| CD79B | FH | MITF | RIT1 | |
| CDC73 | FLCN | MLH1 | RNF43 | |
| CDH1 | FLT3 | MPL | ROS1 | |
| CDK12 | FLT4 | MRE11 | RUNX1 | |
| CDK4 | FOXL2 | MSH2 | SDHB | |
| CDK6 | FUBP1 | MSH6 | SETBP1 | |
| CDKN2A | GALNT12 | MTOR | SETD2 | |
| CDKN2B | GATA1 | MUTYH | SF3B1 | |
| CDKN2C | GATA2 | MYC | SMAD2 | |
| CEBPA | GATA3 | MYCL | SMAD4 | |
| CHEK1 | GEN1 | MYCN | SMARCA4 | |
| CHEK2 | GNA11 | MYD88 | SMARCB1 | |
| CIC | GNAQ | NF1 | SMC1A |
More than 1600 genes in total validated and tested for mutations in cfRNA testing
IMGT repertoire comprises of genes in : IgK, IgL, IgH, T-Receptor A, T-Receptor B, T-Receptor D, and T-Receptor G genes
Genes tested for mutations, fusion, and expression levels in cfRNA testing
| 1-301 | 302-601 | 602-901 | 902-1201 | 1202-1501 |
|---|---|---|---|---|
| ABCC3 | CRKL | HDAC7 | NAV3 | SDHD |
| ABI1 | CRLF2 | HECW1 | NBN | SEC31A |
| ABL1 | CRTC1 | HEPH | NBR1 | SEPTIN2 |
| ABL2 | CRTC3 | HERPUD1 | NCAM1 | SEPTIN5 |
| ABLIM1 | CSF1 | HES1 | NCKIPSD | SEPTIN6 |
| ACACA | CSF1R | HES5 | NCOA1 | SEPTIN9 |
| ACE | CSF3 | HEY1 | NCOA2 | SERP2 |
| ACER1 | CSF3R | HGF | NCOA3 | SERPINE1 |
| ACKR3 | CSNK1G2 | HHEX | NCOA4 | SERPINF1 |
| ACP3 | CSNK2A1 | HIF1A | NCOR2 | SET |
| ACSBG1 | CTCF | HIP1 | NCR1 | SETBP1 |
| ACSL3 | CTDSP2 | HIPK1 | NCSTN | SETD2 |
| ACSL6 | CTLA4 | HIPK2 | NDC80 | SETD7 |
| ACVR1 | CTNNA1 | HLA-DRA | NDE1 | SF3A1 |
| ACVR1B | CTNNB1 | HLA-DRB1 | NDRG1 | SF3B1 |
| ACVR1C | CTNND2 | HLF | NDUFAF1 | SFPQ |
| ACVR2A | CTRB1 | HMGA1 | NEDD4 | SFRP2 |
| ADD3 | CTRB2 | HMGA2 | NEURL1 | SFRP4 |
| ADGRA2 | CTSA | HMGB1 | NF1 | SGK1 |
| ADGRG7 | CUX1 | HNF1A | NF2 | SGPP2 |
| ADM | CXCL8 | HNRNPA2B1 | NFATC1 | SH2D5 |
| AFDN | CXCR4 | HOOK3 | NFATC2 | SH3BP1 |
| AFF1 | CXXC4 | HOXA10 | NFE2L2 | SH3D19 |
| AFF3 | CYFIP2 | HOXA11 | NFIB | SH3GL1 |
| AFF4 | CYLD | HOXA13 | NFKB1 | SH3GL2 |
| AFP | CYP1B1 | HOXA3 | NFKB2 | SHC1 |
| AGR3 | CYP2C19 | HOXA9 | NFKBIA | SHC2 |
| AHCYL1 | DAB2IP | HOXC11 | NFYC | SHTN1 |
| AHI1 | DACH1 | HOXC13 | NGF | SIK3 |
| AHR | DACH2 | HOXD11 | NGFR | SIN3A |
| AIP | DAXX | HOXD13 | NIN | SIRT1 |
| AK2 | DCLK2 | HOXD9 | NIPBL | SKP2 |
| AK5 | DCN | HRAS | NKX2-1 | SLC1A2 |
| AKAP12 | DDB2 | HSP90AA1 | NKX2-5 | SLC34A2 |
| AKAP6 | DDIT3 | HSP90AB1 | NKX3-1 | SLC45A3 |
| AKAP9 | DDR2 | HSPA1A | NOD1 | SLC66A3 |
| AKR1C3 | DDX10 | HSPA1B | NODAL | SLC7A5 |
| AKT1 | DDX20 | HSPA2 | NONO | SLCO1B3 |
| AKT2 | DDX39B | HSPA4 | NOS3 | SLX4 |
| AKT3 | DDX3X | HSPA5 | NOTCH1 | SMAD2 |
| ALDH1A1 | DDX41 | HTRA1 | NOTCH2 | SMAD3 |
| ALDH2 | DDX5 | HUWE1 | NOTCH3 | SMAD4 |
| ALDOC | DDX6 | IBSP | NOTCH4 | SMAD5 |
| ALK | DEK | ICAM1 | NPM1 | SMAD6 |
| AMER1 | DGKB | ICOS | NPM2 | SMAP1 |
| AMH | DGKI | ID1 | NR3C1 | SMARCA1 |
| ANGPT1 | DGKZ | ID3 | NR4A3 | SMARCA4 |
| ANKRD28 | DICER1 | ID4 | NR5A1 | SMARCA5 |
| ANLN | DIRAS3 | IDH1 | NR6A1 | SMARCB1 |
| ANPEP | DIS3L2 | IDH2 | NRAS | SMC1A |
| APC | DKK1 | IDO1 | NRG1 | SMC3 |
| APH1A | DKK2 | IFNG | NSD1 | SMO |
| APLP2 | DKK4 | IFRD1 | NSD2 | SNAPC3 |
| APOD | DLEC1 | IGF1 | NSD3 | SNCG |
| AR | DLL1 | IGF1R | NT5C2 | SNW1 |
| ARAF | DLL3 | IGFBP2 | NTF3 | SNX29 |
| ARFRP1 | DLL4 | IGFBP3 | NTF4 | SNX9 |
| ARG1 | DMRT1 | IGLL5 | NTRK1 | SOCS1 |
| ARHGAP20 | DMRTA2 | IKBKB | NTRK2 | SOCS2 |
| ARHGAP26 | DNAJB1 | IKBKE | NTRK3 | SOCS3 |
| ARHGEF12 | DNM1 | IKZF1 | NUMA1 | SOD2 |
| ARHGEF7 | DNM2 | IKZF2 | NUP107 | SORBS2 |
| ARID1A | DNM3 | IKZF3 | NUP214 | SORT1 |
| ARID2 | DNMT1 | IL12RB2 | NUP93 | SOS1 |
| ARIH2 | DNMT3A | IL13 | NUP98 | SOX10 |
| ARNT | DNTT | IL13RA2 | NUTM1 | SOX11 |
| ARRDC4 | DOCK1 | IL15 | NUTM2A | SOX2 |
| ASMTL | DOT1L | IL1B | NUTM2B | SP1 |
| ASPH | DPM1 | IL1R1 | OCLN | SP3 |
| ASPSCR1 | DPP4 | IL1RAP | OFD1 | SPECC1 |
| ASTN2 | DPYD | IL2 | OGA | SPEN |
| ASXL1 | DST | IL21R | OLIG1 | SPN |
| ATF1 | DTX1 | IL2RA | OLIG2 | SPOP |
| ATF3 | DTX4 | IL3 | OLR1 | SPP1 |
| ATG13 | DUSP2 | IL3RA | OMD | SPRY2 |
| ATG5 | DUSP22 | IL6 | OPN1LW | SPRY4 |
| ATIC | DUSP26 | IL7R | P2RY8 | SPTAN1 |
| ATL1 | DUSP9 | INHBA | PAFAH1B2 | SPTBN1 |
| ATM | E2F1 | INPP4A | PAG1 | SQSTM1 |
| ATP1B4 | EBF1 | INPP4B | PAK1 | SRC |
| ATP6V1G2-DDX39B | ECT2L | INPP5A | PAK3 | SRF |
| ATP8A2 | EDIL3 | INPP5D | PAK5 | SRGAP3 |
| ATR | EDNRB | IQCG | PAK6 | SRRM3 |
| ATRNL1 | EED | IRAG2 | PALB2 | SRSF2 |
| ATRX | EEFSEC | IRF1 | PAPPA | SRSF3 |
| AURKA | EGF | IRF2BP2 | PASK | SS18 |
| AURKB | EGFR | IRF4 | PATZ1 | SS18L1 |
| AUTS2 | EGR1 | IRF8 | PAX3 | SSBP2 |
| AXIN1 | EGR2 | IRS1 | PAX5 | SSX1 |
| AXL | EGR3 | IRS2 | PAX7 | SSX2 |
| B2M | EGR4 | IRS4 | PAX8 | SSX2B |
| B3GAT1 | EIF4A2 | ITGA2B | PBRM1 | SSX4 |
| BACH1 | EIF4E | ITGA5 | PBX1 | SSX4B |
| BACH2 | ELF4 | ITGA7 | PC | ST6GAL1 |
| BAG4 | ELK4 | ITGA8 | PCA3 | STAG2 |
| BAIAP2L1 | ELL | ITGAE | PCBP1 | STAT1 |
| BAP1 | ELN | ITGAM | PCLO | STAT3 |
| BARD1 | ELOVL2 | ITGAV | PCM1 | STAT4 |
| BAX | ELP2 | ITGAX | PCNA | STAT5A |
| BAZ2A | EML1 | ITGB3 | PCSK7 | STAT5B |
| BCAS3 | EML4 | ITGB4 | PDCD1 | STAT6 |
| BCAS4 | EMSY | ITK | PDCD11 | STIL |
| BCL10 | ENG | ITPKA | PDCD1LG2 | STK11 |
| BCL11A | ENPP2 | JAG2 | PDCD6-AHRR | STRN |
| BCL11B | ENTPD1 | JAK1 | PDE4DIP | STX5 |
| BCL2 | EP300 | JAK2 | PDGFA | STYK1 |
| BCL2A1 | EP400 | JAK3 | PDGFB | SUFU |
| BCL2L1 | EPC1 | JARID2 | PDGFD | SUGP2 |
| BCL2L2 | EPCAM | JAZF1 | PDGFRA | SULF1 |
| BCL3 | EPHA10 | JUN | PDGFRB | SUV39H2 |
| BCL6 | EPHA2 | KALRN | PDK1 | SUZ12 |
| BCL7A | EPHA3 | KAT6A | PEG3 | SYK |
| BCL9 | EPHA5 | KAT6B | PER1 | SYP |
| BCOR | EPHA7 | KCNB1 | PFDN5 | TACC1 |
| BCORL1 | EPHB1 | KDM1A | PHB | TACC2 |
| BCR | EPHB6 | KDM2B | PHF1 | TACC3 |
| BDNF | EPO | KDM4C | PHF23 | TAF1 |
| BHLHE22 | EPOR | KDM5A | PHF6 | TAF15 |
| BICC1 | EPS15 | KDM5C | PHOX2B | TAFA2 |
| BIN1 | ERBB2 | KDM6A | PI4KA | TAFA5 |
| BIRC3 | ERBB3 | KDR | PICALM | TAL1 |
| BIRC6 | ERBB4 | KDSR | PIK3CA | TAL2 |
| BLM | ERC1 | KEAP1 | PIK3CB | TAOK1 |
| BMP4 | ERCC1 | KIAA0232 | PIK3CD | TBL1XR1 |
| BMPR1A | ERCC2 | KIAA1549 | PIK3CG | TBX15 |
| BRAF | ERCC3 | KIF5B | PIK3R1 | TBX21 |
| BRCA1 | ERCC4 | KIT | PIK3R2 | TCEA1 |
| BRCA2 | ERCC5 | KLF4 | PIM1 | TCF12 |
| BRD1 | ERCC6 | KLHL6 | PIMREG | TCF3 |
| BRD3 | ERG | KLK2 | PITX2 | TCF7 |
| BRD4 | ERLIN2 | KLK3 | PKM | TCF7L2 |
| BRIP1 | ESR1 | KLK7 | PLA2G2A | TCL1A |
| BRSK1 | ETS1 | KLRC1 | PLA2G5 | TCL1B |
| BRWD3 | ETS2 | KMT2A | PLAG1 | TCL6 |
| BTBD18 | ETV1 | KMT2B | PLAT | TCTA |
| BTG1 | ETV4 | KMT2C | PLAU | TEAD1 |
| BTG2 | ETV5 | KMT2D | PLCB1 | TEAD2 |
| BTK | ETV6 | KNL1 | PLCB4 | TEAD3 |
| BTLA | EVI2A | KPNB1 | PLCG1 | TEAD4 |
| BUB1B | EVI2B | KRAS | PLCG2 | TEC |
| C10orf55 | EWSR1 | KRT1 | PLEKHM2 | TENM1 |
| C11orf1 | EXOSC6 | KRT10 | PLPP3 | TENT5C |
| C11orf54 | EXT1 | KRT16 | PML | TERF1 |
| C2CD2L | EXT2 | KRT17 | PMS1 | TERF2 |
| CACNA1F | EYA1 | KRT19 | PMS2 | TERT |
| CACNA1G | EYA2 | KRT2 | POFUT1 | TET1 |
| CACNA2D3 | EZH2 | KRT5 | POLD1 | TET2 |
| CAD | EZR | KRT6A | POLD4 | TFDP1 |
| CALR | FAF1 | KRT6B | POLR2H | TFE3 |
| CAMK2A | FANCA | KRT8 | POM121 | TFEB |
| CAMK2B | FANCB | KSR1 | POMGNT1 | TFG |
| CAMK2G | FANCC | KTN1 | POSTN | TFPT |
| CAMTA1 | FANCD2 | LAG3 | POT1 | TFRC |
| CANT1 | FANCE | LAMA1 | POU2AF1 | TG |
| CAPRIN1 | FANCF | LAMA5 | POU5F1 | TGFB2 |
| CAPZB | FANCG | LAMP1 | PPARG | TGFB3 |
| CARD11 | FANCI | LAMP2 | PPARGC1A | TGFBI |
| CARM1 | FANCL | LASP1 | PPFIA2 | TGFBR2 |
| CARMIL2 | FANCM | LCK | PPFIBP1 | TGFBR3 |
| CARS1 | FAS | LCP1 | PPM1D | THADA |
| CASP3 | FASLG | LDHA | PPP1CB | THBS1 |
| CASP7 | FBN2 | LDHB | PPP1R13B | THRA |
| CASP8 | FBXO11 | LDHC | PPP1R13L | THRAP3 |
| CAV1 | FBXO31 | LEF1 | PPP2CB | TIAM1 |
| CBFA2T3 | FBXW7 | LEFTY2 | PPP2R1A | TIRAP |
| CBFB | FCER2 | LFNG | PPP2R1B | TLL2 |
| CBL | FCGBP | LGALS3 | PPP2R2B | TLR4 |
| CBLB | FCGR1A | LGR5 | PPP3CA | TLX1 |
| CBLC | FCGR2B | LHFPL3 | PPP3CB | TLX3 |
| CCAR2 | FCGR3A | LHFPL6 | PPP3CC | TMEM127 |
| CCDC28A | FCRL4 | LHX2 | PPP3R1 | TMEM230 |
| CCDC6 | FEN1 | LHX4 | PPP3R2 | TMEM30A |
| CCDC88C | FEV | LIFR | PPP4C | TMPRSS2 |
| CCK | FGF1 | LILRA4 | PRCC | TNC |
| CCL2 | FGF10 | LINGO2 | PRDM1 | TNF |
| CCNA2 | FGF13 | LMBRD1 | PRDM16 | TNFAIP3 |
| CCNB1IP1 | FGF14 | LMO1 | PRDM7 | TNFRSF10B |
| CCNB3 | FGF19 | LMO2 | PRF1 | TNFRSF10D |
| CCND1 | FGF2 | LMO7 | PRG2 | TNFRSF11A |
| CCND2 | FGF23 | LNP1 | PRICKLE1 | TNFRSF14 |
| CCND3 | FGF3 | LOX | PRKACA | TNFRSF17 |
| CCNE1 | FGF4 | LPAR1 | PRKACG | TNFRSF4 |
| CCNG1 | FGF6 | LPP | PRKAR1A | TNFRSF6B |
| CCT6B | FGF8 | LPXN | PRKCA | TNFRSF8 |
| CD14 | FGF9 | LRIG3 | PRKCB | TNFRSF9 |
| CD19 | FGFR1 | LRP1B | PRKCD | TOP1 |
| CD1A | FGFR1OP | LRP5 | PRKCG | TOP2A |
| CD2 | FGFR1OP2 | LRPPRC | PRKDC | TOP2B |
| CD200 | FGFR2 | LRRC37B | PRKG2 | TP53 |
| CD22 | FGFR3 | LRRC59 | PRMT1 | TP53BP1 |
| CD24 | FGFR4 | LRRC7 | PRMT8 | TP63 |
| CD247 | FH | LRRK2 | PROM1 | TP73 |
| CD274 | FHIT | LTBP1 | PRPF40B | TPD52L2 |
| CD28 | FHL2 | LUC7L2 | PRPF8 | TPM3 |
| CD33 | FIP1L1 | LYL1 | PRRX1 | TPM4 |
| CD34 | FLCN | LYN | PRRX2 | TPO |
| CD36 | FLI1 | MACROD1 | PRSS3 | TPR |
| CD38 | FLNA | MAD2L1 | PRSS8 | TRAF2 |
| CD3D | FLNC | MADD | PSD3 | TRAF3 |
| CD3E | FLT1 | MAF | PSEN1 | TRAF5 |
| CD3G | FLT3 | MAFB | PSIP1 | TRHDE |
| CD4 | FLT3LG | MAGED1 | PSMD2 | TRIM24 |
| CD40 | FLT4 | MAGEE1 | PTBP1 | TRIM27 |
| CD40LG | FLYWCH1 | MALT1 | PTCH1 | TRIM33 |
| CD44 | FNBP1 | MAML1 | PTCRA | TRIP11 |
| CD47 | FOS | MAML2 | PTEN | TRPS1 |
| CD5 | FOSB | MAP2 | PTGS2 | TSC1 |
| CD52 | FOSL1 | MAP2K1 | PTK2 | TSC2 |
| CD58 | FOXL2 | MAP2K2 | PTK2B | TSHR |
| CD59 | FOXO1 | MAP2K3 | PTK7 | TTF1 |
| CD68 | FOXO3 | MAP2K4 | PTPA | TTK |
| CD7 | FOXO4 | MAP2K5 | PTPN11 | TTL |
| CD70 | FOXP1 | MAP2K6 | PTPN2 | TUSC3 |
| CD74 | FOXP3 | MAP2K7 | PTPN6 | TYK2 |
| CD79A | FRK | MAP3K1 | PTPRA | TYMS |
| CD79B | FRMPD4 | MAP3K14 | PTPRC | U2AF1 |
| CD81 | FRS2 | MAP3K6 | PTPRK | U2AF2 |
| CD8A | FRYL | MAP3K7 | PTPRO | UBE2B |
| CD8B | FSTL3 | MAPK1 | PTPRR | UBE2C |
| CD9 | FUS | MAPK3 | PTTG1 | UFC1 |
| CDC14A | FUT1 | MAPK8 | RABEP1 | UFM1 |
| CDC14B | FUT4 | MAPK8IP2 | RAC1 | UPK3A |
| CDC25A | FZD10 | MAPK9 | RAC2 | USP16 |
| CDC25C | FZD2 | MAPRE1 | RAC3 | USP42 |
| CDC42 | FZD3 | MATK | RAD21 | USP5 |
| CDC73 | FZD6 | MAX | RAD50 | USP6 |
| CDH1 | FZD7 | MB21D2 | RAD51 | USP7 |
| CDH11 | FZD8 | MBNL1 | RAD51B | UTP4 |
| CDK1 | GAB1 | MBTD1 | RAD51C | VCAM1 |
| CDK12 | GABRG2 | MCAM | RAD51D | VEGFA |
| CDK2 | GADD45B | MCL1 | RAD52 | VEGFC |
| CDK4 | GANAB | MCM3AP | RAF1 | VEGFD |
| CDK5RAP2 | GAS1 | MDC1 | RALGDS | VGLL3 |
| CDK6 | GAS7 | MDH1 | RANBP17 | VHL |
| CDK7 | GATA1 | MDM2 | RANBP2 | VSIR |
| CDK8 | GATA2 | MDM4 | RAP1GDS1 | VTI1A |
| CDK9 | GATA3 | MDS2 | RARA | WASF2 |
| CDKL5 | GATA6 | MEAF6 | RASAL1 | WDCP |
| CDKN1A | GBP1 | MECOM | RASGEF1A | WDFY3 |
| CDKN1B | GBP2 | MED12 | RASGRF1 | WDR1 |
| CDKN1C | GDF6 | MEF2B | RASGRF2 | WDR18 |
| CDKN2A | GFAP | MEF2C | RASGRP1 | WDR70 |
| CDKN2B | GHR | MEF2D | RB1 | WDR90 |
| CDKN2C | GID4 | MELK | RBM15 | WEE1 |
| CDKN2D | GIT2 | MEN1 | RBM6 | WIF1 |
| CDX1 | GLI1 | MET | RCHY1 | WNT10A |
| CDX2 | GLI3 | METTL18 | RCOR1 | WNT10B |
| CEACAM8 | GMPS | METTL7B | RCSD1 | WNT11 |
| CEBPA | GNA11 | MFNG | RECQL4 | WNT16 |
| CEBPB | GNA12 | MGMT | REEP3 | WNT2B |
| CEBPD | GNA13 | MIB1 | REG3A | WNT3 |
| CEBPE | GNAI1 | MIPOL1 | RELA | WNT4 |
| CENPF | GNAQ | MITF | RELN | WNT5B |
| CENPU | GNAS | MKI67 | RERG | WNT6 |
| CEP170B | GNG4 | MLANA | RET | WNT7B |
| CEP57 | GOLGA5 | MLF1 | RGS7 | WNT8B |
| CEP85L | GOPC | MLH1 | RHBDF2 | WRN |
| CHCHD7 | GOSR1 | MLLT1 | RHOA | WSB1 |
| CHD2 | GOT1 | MLLT10 | RHOD | WT1 |
| CHD6 | GPC3 | MLLT11 | RHOH | WWOX |
| CHEK1 | GPHN | MLLT3 | RICTOR | WWTR1 |
| CHEK2 | GPR34 | MLLT6 | RMI2 | XBP1 |
| CHIC2 | GRB10 | MME | RNF213 | XIAP |
| CHL1 | GRB2 | MMP7 | RNF217-AS1 | XKR3 |
| CHMP2B | GRHPR | MMP9 | RNF43 | XPA |
| CHN1 | GRID1 | MN1 | ROBO1 | XPC |
| CHST11 | GRIN2A | MNAT1 | ROBO2 | XPO1 |
| CHUK | GRIN2B | MNX1 | ROS1 | XRCC6 |
| CIC | GRM1 | MPL | RPA3 | YAP1 |
| CIITA | GRM3 | MPO | RPL21 | YPEL5 |
| CILK1 | GSK3B | MRE11 | RPL22 | YTHDF2 |
| CIP2A | GSN | MRTFA | RPN1 | YWHAE |
| CIT | GTF2I | MRTFB | RPN2 | YY1AP1 |
| CKB | GTSE1 | MS4A1 | RPS21 | ZAP70 |
| CKS1B | GYPA | MSH2 | RPS6KA1 | ZBTB16 |
| CLP1 | GZMA | MSH3 | RPS6KA2 | ZC3H7A |
| CLTA | GZMB | MSH6 | RPS6KA3 | ZC3H7B |
| CLTC | H1-2 | MSI2 | RPTOR | ZFP64 |
| CLTCL1 | H1-3 | MSN | RREB1 | ZFPM2 |
| CMKLR1 | H1-4 | MTAP | RRM1 | ZFTA |
| CNBP | H2AC11 | MTCP1 | RRM2B | ZFYVE19 |
| CNOT2 | H2AC16 | MTOR | RTEL1 | ZIC2 |
| CNTN1 | H2AC17 | MTUS2 | RTEL1-TNFRSF6B | ZMIZ1 |
| CNTRL | H2AC6 | MUC1 | RTL8B | ZMYM2 |
| COG5 | H2AX | MUC16 | RTN3 | ZMYM3 |
| COL11A1 | H2BC11 | MUTYH | RUNX1 | ZMYND11 |
| COL1A1 | H2BC12 | MYB | RUNX1T1 | ZNF207 |
| COL1A2 | H2BC17 | MYBL1 | RUNX2 | ZNF217 |
| COL3A1 | H2BC4 | MYC | RYR3 | ZNF24 |
| COL6A3 | H2BC5 | MYCL | S1PR2 | ZNF331 |
| COL9A3 | H3-3A | MYCN | SARNP | ZNF384 |
| COMMD1 | H3C2 | MYD88 | SATB2 | ZNF444 |
| COX6C | H4C9 | MYH11 | SBDS | ZNF521 |
| CPNE1 | HAS2 | MYH9 | SCGB2A2 | ZNF585B |
| CPS1 | HAVCR2 | MYO18A | SCN8A | ZNF687 |
| CPSF6 | HDAC1 | MYO1F | SDC1 | ZNF703 |
| CRADD | HDAC2 | NAB2 | SDC4 | ZRSR2 |
| CREB1 | HDAC3 | NACA | SDHA | |
| CREB3L1 | HDAC4 | NAMPT | SDHAF2 | |
| CREB3L2 | HDAC5 | NAPA | SDHB | |
| CREBBP | HDAC6 | NAPSA | SDHC |